With larger datasets, UMAP higher captures multiple scales of population construction; nice-scale patterns might be hidden or cut up with other strategies, and these are of curiosity when the range of populations is diverse, when there are admixed populations, or when inspecting relationships between genotypes, phenotypes, and/or geography. Population construction can be a problem for affiliation studies, similar to case-control research, קרקעות where the affiliation between the trait of curiosity and locus may very well be incorrect. For instance, in a study population of Europeans and East Asians, an affiliation […]
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